Higher rate of local recurrence in sinonasal squamous cell carcinoma arising from inverted papilloma compared to de novo tumours
Volume: 64 - Issue: 1
First page: 142 - Last page: 144
M-H. Dong - Y-W. Chen - Y-W. Huang - L-T. Hung - C-F. Yeh - M-Y. Lan - Y-T. Chao
DOI: 10.4193/Rhin25.283
Squamous cell carcinoma (SCC) is the most common histological subtype of sinonasal malignancies. Due to non-specific symptoms, sinonasal SCC (SNSCC) is often diagnosed late, posing challenges for management. SNSCC can arise de novo (DN-SCC) or from the malignant transformation of inverted papilloma (IP-SCC). Prior studies have reported inconsistent outcomes comparing these two subtypes. This study compares recurrence patterns and survival outcomes of DN-SCC and IP-SCC, identifies predictors of recurrence and survival, and aims to inform clinical decision-making and patient counselling.
Rhinology 64 - 1: 142-144, 2026
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