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Nasopharyngeal endoscopic resection in the management of selected malignancies: ten-year experience

Volume: 48 - Issue: 1

First page: 84 - Last page: 89

P. Castelnuovo - I. Dallan - M. Bignami - P. Battaglia - S. Mauri - A. Bolzoni Villaret - A. Bizzoni - D. Tomenzoli - P. Nicolai

DOI: 10.4193/Rhin09.079

OBJECTIVE: To evaluate the feasibility of endoscopic surgery in the management of selected nasopharyngeal cancers. Three different types of nasopharyngeal endoscopic resections (NER) are described.
METHOD OF STUDY: From January 1997 to October 2008, 17 consecutive patients (mean age: 50 years) with previously untreated (5) or recurrent nasopharyngeal tumours (12) were treated with curative intent by pure endoscopic resection. The extent of surgical resection was classified as follows: type 1 NER: resection limited to the postero-superior nasopharyngeal wall; type 2 NER: resection superiorly extended to the sphenoid sinus; type 3 NER: resection with lateral extension including the cartilaginous portion of the Eustachian tube and parapharyngeal space.
RESULTS: Type 1 NER was performed in 4 cases, type 2 in 6, and type 3 in 7. No intra- or postoperative complications were observed. Mean hospitalization time was 4 days (range, 1-7). Follow-up ranged from 10 to 138 months (mean, 41,2 ± 38). At the time of writing, 12 (71%) patients were free of disease, 3 (17%) alive with disease, and 2 (12%) dead of disease.
CONCLUSIONS: NER is a feasible surgical technique that can be tailored in relation to tumour extension. Larger series and longer follow-up are needed to further validate the long-term results.

Rhinology 48 - 1: 84-89, 2010

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