Buy article

Does time from previous surgery predict subsequent treatment failure in Chronic Rhinosinusitis with Nasal Polyps?

Volume: 59 - Issue: 3

First page: 277 - Last page: 283

C. Hopkins - V. Lund

Introduction: When considering the introduction of biological treatments for Chronic Rhinosinusitis with nasal polyps (CRSwNP), treatment guidelines must consider not only which patients will best respond to biologicals, but also which patients derive least benefit from current treatment pathways. Using data collected as part of the National Audit of Surgery for Chronic Rhinosinusitis and Nasal Polyps, we sought to evaluate if patients with a history of prior surgery are more likely to need a further revision operation, and whether the interval between surgery may help predict the need for further surgical intervention.
Methods: In the original study, patients were prospectively and consecutively enrolled at the time of sinus surgery in multiple centres in England and Wales. Follow-up captured symptomatic outcomes and revision surgery rates at 3, 12, 36 and 60 months after surgery. Revision surgery rates 5 years after the index procedure, in patients with CRSwNP were analysed with regards to baseline demographics.
Results: Complete data were available for 980 subjects, with a 5 year revision rate of 15.1%. 45.9% had a history of previous surgery before the index procedure, and this group had significantly higher rates of additional surgery compared with those undergoing their first sinus surgery (20.2% versus 9.8%). Patients with an interval of 3 years or less between their previous surgery and the index procedure had the highest rates of further surgery. In a multiple regression, time interval between previous operations was a better prediction of subsequent revision surgery than asthma. Having N-ERD was the strongest predicator of need for further surgery while more extensive surgery was associated with lower revision rates.
Conclusions: Patients presenting with a symptomatic recurrence within 3 years of surgery have a high risk of treatment failure, defined as the need for further surgery. Time to failure after previous surgery may be used to help select patients who may not benefit from current treatment pathways and may be good candidates for alternative strategies, including biologicals.

Rhinology 59-3: 277-283, 2021

To see the issue content and the abstract you do not have to login

Please login to download the full articles

If you do not have a subscription to Rhinology please consider taking one.

Click here to become a member of the European Rhinologic Society and a subscriber to the journal `RHINOLOGY`, from 2023. Subscription including membership fee: Euro 135.-

  1. Situs Slot KayaMendadak88
  2. Situs Slot Online Terbaik Dan Terpercaya No 1
  3. Slot Gacor
  4. Slot Terbaru: https://www.shaptahik.com/slot-terbaru.php
  5. Slot Pragmatic Play
  6. Situs Slot Online Terpercaya
  7. Kumpulan Situs Judi Slot Terpercaya
  8. Game Slot Online
  9. Judi Slot Online Jackpot Terbesar
  10. Situs Judi Slot Online Terpercaya 2021
  11. Situs Slot Online Indonesia
  12. SLOT88
  13. RAJASLOTXO
  14. Slot Joker123
  15. Situs Slot Online Terbaik
  16. Daftar Situs Slot Online
  17. Agen Slot Online Resmi
  18. Slot Deposit Pulsa
  19. Situs Slot Gacor
  20. Situs Judi Slot Online Terbaik & Judi Online 2021
  21. Agen Slot Online Terpercaya
  22. Daftar Situs Judi Slot Terbaik Dan Terpercaya No 1
  23. Pragmatic Play Indonesia
  24. Daftar Situs Judi Slot Online Gampang Menang Terbaik 2021
  25. AloJudi Slot
  26. KayaMendadak88 Slot
  27. Situs Judi Slot Online: http://happy.daa.jp/slot-online/
  28. Situs Judi Slot Online Joker Slot Gaming
  29. Situs Slot Gacor 2022
  30. Slot Gacor Gampang Menang
  31. Link Alternatif: https://nimafadavibeats.com/
  32. Situs Judi Slot Online Indonesia: https://hgj.nbc.mybluehost.me/
  33. Situs Judi Slot Mudah Menang
  34. Situs Slot Online Terbaik dan Terpercaya
  35. Situs Judi Slot Online Terpercaya
  36. slot
  37. Situs Judi Slot Online Jackpot Terbesar
  38. Situs Judi Slot Terbaik Dan Terpercaya No 1
  39. Judi Slot Online Jackpot Terbesar Gampang Menang
  40. Slot Online Terlengkap
  41. Slot Pulsa
  42. Slot Deposit DANA
  43. SLOT88 Pulsa
  44. Situs Judi Online Resmi Aman Dan Terpercaya 2022
  45. https://www.nubekasi.id/
  46. Forum Slot Online Indonesia
  47. Daftar Terbaru Situs Judi Slot Online Terpercaya 2022
  48. Situs Judi Slot Online Indonesia Terpercaya
  49. Situs Judi Slot Online Terpercaya di Indonesia 2022
  50. situs judi slot gacor online terpercaya
  51. Situs Judi Slot Online Terbaik dan Terpercaya 2022
  52. Joker123 Slot
  53. Daftar Situs Judi Slot Online Deposit Pulsa Terbaik
  54. Daftar Situs Judi Slot Online Gacor Gampang Menang 2022
  55. Mesin slot gacor 88
  56. Mesin slot
  57. Slot Hacker
  58. Situs Judi Slot Online Resmi 2021
  59. Slot Via Dana
  60. Situs Judi Slot Online Terpercaya No 1
  61. Link Alternatif Joker123
  62. Situs Judi Slot Mudah Menang