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Volume: 48 - Issue: 1

First page: 71 - Last page: 76

A. Salami - M. Dellepiane - F. Strinati - L. Guastini - R. Mora

INTRODUCTION: The aim of this study was to evaluate the efficiency of sulphurous thermal water
in the treatment of chronic rhinosinusitis (CRS).
Methods: Eighty patients with CRS were included and randomly assigned into two groups. Patients underwent a 12-day course of warm vapour inhalations and nasal irrigations with sulphurous thermal water in group A, and a physiological solution in group B.
RESULTS: Compared with group B, in group Athe results were as follows: serum concentration of IgE was significantly lower (p smaller than 0.05) 12 days (76.27 plusmn 26.3 mg/dl vs. 97.44 plusmn 45.4) and 3 months after the beginning of the treatment (75.48 plusmn 26.1 mg/dl vs. 98.37 plusmn 41.4); IgA titers were not significantly higher 12 days (231.09 ± 120.3 mg/dl vs. 220.44 plusmn 114.4 mg/dl) and 3 months after the beginning of the treatment (235.44 plusmn 118.5 mg/dl vs. 214.51 plusmn 111.8 mg/dl); VAS scores were significantly (p smaller than 0.05) improved at 12 days (1.7 plusmn 0.18 vs. 6.9 plusmn 0.51) and 3 months after the start (1.8 plusmn 0.22 vs. 7.1 plusmn 0.59); NMTT was normal at 12 days (11.54 plusmn 1.59 min vs. 17.38 plusmn 1.83 min) and 3 months after the beginning of the treatment (11.46 plusmn 2.07 min vs. 17.43 plusmn 2.01 min); total nasal resistances were significantly (p smaller than 0.05) decreased at 12 days and 3 months.
CONCLUSION: Our results indicate the efficiency and applicability of sulphurous thermal water in the treatment of CRS.

Rhinology 48-1: 71-76, 2010