To see the issue content and the abstract you do not have to login
Please login to download the full articles

Emailadres
Password
Lost password?      Click here!

If you do not have a subscription to Rhinology please consider to take one.
Click here to become a member of the European Rhinologic Society and a subscriber to the journal `RHINOLOGY`, beginning 2019. Subscription including membership fee: Euro 139.-

If you only want to buy this paper please click here
The price of the paper is 25 euro.


Similar survival outcome after endoscopic and open approaches for sinonasal mucosal melanoma

Volume: - Issue:

Firstpage: 0 - Lastpage: 0

M. Lundberg - A. Haapaniemi - J. Hagstrom - S. Juteau - M. Hernberg - A.A. Makitie - S.I. Vento

BACKGROUND: To describe a cohort of sinonasal mucosal melanoma (SNMM) patients, and to assess if choice of surgical approach (open versus endoscopic) has impact on survival.
METHODOLOGY: Adequate data on clinical presentation, treatment, and recurrence pattern were available for 58 consecutive patients treated for SNMM at the Helsinki University Hospital (HUH) between 1983 and 2016.
RESULTS: The 5-year disease-specific survival (DSS) was 27% and overall survival 25% for the whole cohort. The 3-year DSS for patients treated with curative intent with endoscopic surgery was comparable to open surgery (56% and 51%, respectively). Patients with tumours arising from the paranasal sinuses and patients with Stage IV disease had significantly worse prognosis compared with other locations and Stage III patients. All patients who had disease persistence at three months after primary treatment succumbed to SNMM. Post-operative radiotherapy did not affect survival significantly, but a trend towards improved local control was observed.
CONCLUSIONS: Local control after endoscopic surgery was comparable to open surgery. Small tumours without local or locoregional spread had improved prognosis, independent of surgical approach. Disease persistence after treatment with curative intent led to death invariably.

M. Lundberg - A. Haapaniemi - J. Hagstrom - S. Juteau - M. Hernberg - A.A. Makitie - S.I. Vento - Similar survival outcome after endoscopic and open approaches for sinonasal mucosal melanoma
Rhinology -: 0-0, 0000